Chapter 6 226 Table S1 (part 1). Continued Diagnosis Driver mutation (TISSUE) EGFR T790M detected in tumor tissue Reason for pleurocentesis NKI-48 unknown origin KRAS therapeutic NKI-49 NSCLC EGFR exon 19 del therapeutic NKI-50 NSCLC KRAS therapeutic NKI-51 NSCLC EGFR exon 19 del therapeutic NKI-52 colon carcinoma KRAS therapeutic NKI-53 NSCLC KRAS diagnostic NKI-54 colon carcinoma KRAS diagnostic NKI-55 NSCLC KRAS diagnostic NKI-56 NSCLC KRAS diagnostic Table S1 (part 2). Concentrations of the original driver mutation and EGFR T790M in the supernatant and/or the cell pellet measured by ddPCR Supernatant Original driver copies /ml WT original driver copies /ml EGFR T790M copies /ml WT EGFR T790M copies /ml NKI-1 369 781 72 1298 NKI-2 28820 80300 NKI-3 2110 7150 NKI-4 103 418 NKI-5 13662 27588 12474 26136 NKI-6 594 1474 NKI-7 3018 11242 NKI-8 8716 4906 NKI-9 881 4077 NKI-10 2160 13772 0 13200 NKI-11 2231240 2063600 1196800 3080000 NKI-12 90 2948 0 3322 NKI-13 23835 123464 0 155100 NKI-14 99568 17248 0 112068
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