116 Chapter 5 Table S6. Patient characteristics of cases categorized into three groups according to the day of onset of Intensive Care Unit-acquired pneumonia ICU-A pneumonia 0-5 days (n = 105) ICU-A pneumonia 6-9 days (n = 69) ICU-A pneumonia >10 days (n = 68) P value Baseline data Age, yr, mean (SD) 63.7 (16.6) 62.0 (14.1) 64.7 (15.4) 0.585 Female sex, n (%) 67 (63.8) 56 (81.2) 44 (64.7) 0.035 Body Mass Index, mean (SD) 26.8 (5.9) 27.0 (4.7) 28.3 (7.9) 0.282 Charlson Comorbidity Index, median (IQR) 3.0 [2.0, 5.0] 3.0 [1.0, 4.0] 4.0 [2.0, 5.0] 0.285 Origin prior to ICU admission, n (%) 0.352 Home 63 (60.0) 33 (47.8) 32 (47.1) General ward 27 (25.7) 19 (27.5) 22 (32.4) Long term facility 0 (0.0) 0 (0.0) 1 (1.5) Other ICU 12 (11.4) 13 (18.8) 12 (17.6) Other 3 (2.9) 4 (5.8) 1 (1.5) Primary reason for ICU admission, n (%) 0.928 Medical 50 (47.6) 33 (47.8) 33 (48.5) Surgical, cardiothoracic 3 (2.9) 2 (2.9) 1 (1.5) Surgical, other 30 (28.6) 17 (24.6) 22 (32.4) Trauma 22 (21.0) 17 (24.6) 12 (17.6) Colonized with Staphylococcus aureus on admission, n (%) 60 (57.1) 34 (49.3) 35 (51.5) 0.559 Pneumonia on ICU admission, n (%) 17 (16.2) 11 (15.9) 18 (26.5) 0.181 APACHE IV, mean (SD) 76.0 (37.2) 65.2 (37.0) 76.1 (34.7) 0.116 Laboratory values at ICU admission White blood cells, 109/L, median (IQR) 13.2 [9.0, 19.5] 13.3 [9.8, 18.0] 11.4 [7.8, 15.8] 0.097 Neutrophils, 109/L, median (IQR) 11.3 [7.4, 14.9] 12.1 [8.2, 14.3] 10.2 [6.9, 13.6] 0.184 Monocytes, 109/L, median (IQR) 0.7 [0.5, 1.0] 0.7 [0.6, 1.1] 0.5 [0.3, 0.9] 0.031 Lymphocytes, 109/L, median (IQR) 1.0 [0.6, 1.3] 0.9 [0.5, 1.2] 0.7 [0.5, 0.9] 0.040
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