203 Classifying study participants in clinical trials Exacerbation asthma Exacerbation asthma, thoracic pain of unknown origin* Exacerbation asthma, thoracic pain of unknown origin* 1 Exacerbation COPD Exacerbation COPD, cardiac failure Exacerbation COPD, cardiac failure 1 Extrathoracic pathology Extrathoracic pathology, other LRTI 1 Fever of unknown origin Fever of unknown origin, extrathoracic pathology* 1 Influenza A/B Influenza A/B, cardiac failure Influenza A/B 1 Influenza A/B Influenza A/B, extrathoracic pathology* 1 Influenza A/B Influenza A/B, other LRTI* 1 Influenza A/B, exacerbation COPD Influenza A/B, exacerbation COPD, ACS with elevated troponin levels Influenza A/B, exacerbation COPD 1 Influenza A/B, other thoracic pathology Influenza A/B, other thoracic pathology, exacerbation COPD 1 Other LRTI, exacerbation COPD Exacerbation COPD 1 Sinusitis, exacerbation asthma Exacerbation asthma 1 Thoracic pain of unknown origin Thoracic pain of unknown origin, exacerbation CF* Thoracic pain of unknown origin 1 Thoracic pain of unknown origin Thoracic pain of unknown origin, exacerbation COPD Thoracic pain of unknown origin 1 URTI URTI, exacerbation COPD 1 Disagreement 13 Single label cases 6 Extrathoracic pathology Fever of unknown origin 2 AC Pulmonary embolism 1 ACS with elevated troponin levels ACS with elevated troponin levels Other thoracic pathology 1 Fever of unknown origin Extrathoracic pathology* 1 Thoracic pain of unknown origin* Extrathoracic pathology* Thoracic pain of unknown origin* 1 Multiple label cases 7 AC Aspiration pneumonia, extrathoracic pathology 1 AC CAP, influenza A/B 1 8
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