Tjitske van Engelen

218 Chapter 9 Table 2. Diagnoses at ED discharge and at Day 28a b ULDCT (n = 1161) CXR (n = 1151) Difference (95% CI) Diagnosis Diagnosis at ED discharge Diagnosis at Day 28 Diagnosis at ED discharge Diagnosis at Day 28 Diagnosis at ED discharge Diagnosis at Day 28 Communityacquired pneumonia 255 (22.0) 225 (19.4) 189 (16.4) 169 (14.7) 5.5 (2.3 to 8.8) 4.7 (1.6 to 7.8) Lower respiratory tract infection other than pneumonia 101 (8.7) 121 (10.4) 100 (8.7) 116 (10.1) 0 (-2.3 to 2.3) 0.3 (-2.1 to 2.8) COPD exacerbation 83 (7.1) 116 (10.0) 72 (6.3) 127 (11.0) 0.8 (-1.1 to 2.9) -1.0 (-3.5 to 1.5) (Possible) influenza A/Bc 74 (6.4) 96 (8.3) 37 (3.2) 73 (6.3) 3.2 (1.4 to 4.9) 1.9 (-0.2 to 4.0) Congestive heart failure 66 (5.7) 66 (5.7) 87 (7.6) 110 (9.6) -1.9 (-3.9 to 1.5) -3.9 (-6.0 to -1.7) Asthma exacerbation 51 (4.4) 75 (6.5) 34 (3.0) 49 (4.3) 1.4 (-0.1 to 3.0) 2.2 (0.4 to 4.0) Upper respiratory tract infection 49 (4.2) 52 (4.5) 48 (4.2) 64 (5.6) 0 (-1.6 to 1.7) -1.1 (-2.9 to 0.7) Healthcare-associated pneumonia 4 (0.3) 50 (4.3) 8 (0.7) 37 (3.2) -0.4 (-0.9 to 0.2) 1.1 (-0.5 to 2.6) Extra-thoracic pathology 259 (22.3) 299 (25.8) 246 (21.4) 338 (29.4) 0.9 (-2.4 to 4.3) -3.6 (-7.3 to 0.03) Thoracic pain of unknown origin 110 (9.5) 122 (10.5) 112 (9.7) 135 (11.7) -0.3 (-2.7 to 2.2) -1.2 (-3.8 to 1.3) Fever of unknown origin 111 (9.6) 53 (4.6) 85 (7.4) 46 (4.0) 2.2 (-0.1 to 4.4) 0.6 (-1.1 to 2.2) Other thoracic pathology 57 (4.9) 60 (5.2) 66 (5.7) 63 (5.5) -0.8 (-2.7 to 1.0) -0.3 (-2.1 to 1.5) No definite diagnosis yet 78 (6.7) - 108 (9.4) - -2.7 (-4.9 to 0.5) - COPD= Chronic obstructive pulmonary disease. a Values are numbers (percentages) unless otherwise noted. b Only diagnoses that occurred in more than 50 patients either at ED discharge or at Day 28 are reported in this table. See Supplementary Table S6 for the results of all 32 diagnostic categories. Patients could have more than one diagnosis. c (Possible) influenza A/ B: at ED discharge a diagnosis of possible influenza was assigned if a patient was treated for influenza A/B awaiting the results of the PCR test. At day 28 diagnosis of influenza A/B was assigned to PCR positive patients accordingly.

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