223 Low-dose-CT versus X-ray in patients suspected of pulmonary disease Funding The research was funded by an innovation grant of the Amsterdam University Medical Centres (Amsterdam UMC), location Academic Medical Centre (AMC), University of Amsterdam and a Health Care Efficiency Program grant of the Netherlands Organization for Health Research and Development (ZonMW: 843001806). Amsterdam UMC and ZonMW had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data, preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication. Competing Interests All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr. Stoker reported receipt of an innovation grant of the Amsterdam UMC, location AMC, University of Amsterdam and a grant of Health Care Efficiency Program of the Netherlands Organization for Health Research and Development (ZonMW:843001806). Dr. Kanglie reports to have received personal fees from the before mentioned grants. Dr. Middeldorp reports to have received grants and personal fees from Bayer, BMS Pfizer, Boehringer Ingelheim, Daiichi Sankyo, Portola, GSK, Aspen. Dr. van Engelen reports to have received a personal Fee, PhD Scholarship grant, from Amsterdam UMC. The other authors reported no conflict of interest. Data availability statement The data that support the findings of this study are available from the corresponding author, IAHvdB, upon reasonable request. Ethics statements Patient consent for publication Not required. Ethics approval Ethical approval by the medical ethical commission is obtained on November 24, 2016 (NL57923.018.16). Registration Netherlands Trial Register, number NTR6163, NTR (trialregister.nl). 9
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