233 Low-dose-CT versus X-ray in patients suspected of pulmonary disease Table S1 Excluded patients Amsterdam UMC and Spaarne Gasthuis (SG) Amsterdam UMC Spaarne Gasthuisa Assessed for eligibility Total (n = 4807) ULDCT (n = 1887) CXR (n = 1981) ULDCT (n = 475) CXR (n = 464) Randomised 2418 881 890 327 320 Excludedb 2389 1006 1091 148 144 Not meeting inclusion criteria 1286 (26.8) 611 (32.4) 617 (31.1) 19 (4.0) 39 (8.4) Earlier participants 572 294 272 3 3 Barriers to follow-up data collection 232 85 130 7 10 Life expectancy less than one month 192 68 104 7 13 Incapacitated patients 178 84 80 2 12 Unable to undergo ULDCT or CXR 107 79 28 0 0 Pregnancy 5 1 3 0 1 Declined participation 237 (4.9) 119 (6.3) 115 (5.8) 2 (0.4) 1 (0.2) Other reasons 866 (18.0) 276 (14.6) 359 (18.1) 127 (26.7) 104 (22.4) Unknown 731 202 349 76 104 Transport problems 4 0 3 1 0 Waiting time too long 6 0 6 0 0 CT scanner not available 124 74 0 50 0 Electronic patient record error 1 0 1 0 0 ULDCT: Ultra-low-dose chest computed tomography, CXR: Chest X-ray. a Due to privacy regulations the total number of patients assessed for eligibility, and the total number of patients excluded for randomization are incomplete. These numbers are composed of complete data (Amsterdam UMC, location AMC) and data from a random sample of non-included patients (Spaarne Gasthuis). b Values are numbers (percentages). 9
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