Tjitske van Engelen

239 Low-dose-CT versus X-ray in patients suspected of pulmonary disease Table S5 Baseline characteristics completea Characteristics ULDCT (n = 1208) CXR (n = 1210) Mean age (SD)b, y 59.0 (18.1) 59.0 (18.6 ) Female sex 613 (50.7) 587 (48.5) Comorbidity Charlson Comorbidity Indexc (IQR) 3.0 (1.0-5.0) 3.0 (1.0-5.0) Immunocompromised 285 (23.6) 246 (20.3) Malignancyb 229 (19.0) 222 (18.3) Solid tumourd Total 151 (13) 168 (14.0) Localized 88 (7.3) 92 (7.6) Metastasized 63 (5.2) 76 (6.3) Malignant lymphomad 46 (3.8) 33 (2.7) Leukemiad 32 (2.6) 21 (1.7) Diabetesb 230 (19.0) 245 (20.2) No end organ damagee 173 (14.3) 177 (14.6) With end organ damagee 57 (4.7) 68 (5.6) Pulmonary disease Chronic obstructive pulmonary diseasec 175 (14.5) 179 (14.8) Asthma 141 (11.7) 109 (9.0) Interstitial lung disease 29 (2.4) 28 (2.3) Cystic fibrosis 14 (1.2) 14 (1.2) Cardiac disease Myocardial infarctionb 159 (13.2) 169 (14.0) Chronic cardiac failureb 98 (8.1) 98 (8.1) Neurological diseaseb 140 (11.6) 149 (12.3) Cerebrovascular diseaseb 128 (10.6) 133 (11.0) Dementiab 8 (0.7) 7 (0.6) Hemiplegiab 4 (0.3) 9 (0.7) Kidney diseaseb 104 (8.6) 119 (9.8) Thromboembolic disease 92 (7.6) 107 (8.8) Peripheral vascular diseaseb 66 (5.5) 88 (7.3) Liver disease 44 (3.6) 46 (3.8) Cirrhosis 24 (2.0) 22 (1.8) Chronic hepatitis 20 (1.7) 24 (2.0) ULDCT: Ultra-low-dose chest computed tomography, CXR: Chest X-ray, IQR: interquartile range a Values are numbers (percentages) unless otherwise specified. 9

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