Tjitske van Engelen

240 Chapter 9 b Variables included in the Charlson Comorbidity Index c Charlson Comorbidity Index, excluding AIDS. Predicts 10-year survival in patients with multiple comorbidities d Within the past 5 years, except for chronic lymphatic leukaemia e End organ damage: retinopathy, neuropathy, or nephropathy Table S6 Diagnosis at ED discharge and Day 28 diagnosis completea b Day 28 diagnosis ULDCT (n = 1161) CXR (n = 1151) Diagnosis at ED discharge Diagnosis at Day 28 Diagnosis at ED discharge Diagnosis at Day 28 Extra-thoracic pathology 259 (22.3) 299 (25.8) 246 (21.4) 338 (29.4) Community-acquired pneumonia 255 (22.0) 225 (19.4) 189 (16.4) 169 (14.7) Thoracic pain of unknown origin 110 (9.5) 122 (10.5) 112 (9.7) 135 (11.7) Fever of unknown origin 111 (9.6) 53 (4.6) 85 (7.4) 46 (4.0) Lower respiratory tract infection other than pneumonia 101 (8.7) 121 (10.4) 100 (8.7) 116 (10.1) COPD exacerbation 83 (7.1) 116 (10.0) 72 (6.3) 127 (11.0) No definite diagnosis yet 78 (6.7) - 108 (9.4) - Congestive heart failure 66 (5.7) 66 (5.7) 87 (7.6) 110 (9.6) (Possible) influenza A/Bc 53 (4.6) 96 (8.3) 22 (1.9) 73 (6.3) Other thoracic pathology 57 (4.9) 60 (5.2) 66 (5.7) 63 (5.5) Asthma exacerbation 51 (4.4) 75 (6.5) 34 (3.0) 49 (4.3) Upper respiratory tract infection 49 (4.2) 52 (4.5) 48 (4.2) 64 (5.6) Healthcare-associated pneumonia 4 (0.3) 50 (4.3) 8 (0.7) 37 (3.2) Dyspnoea of unknown origin 32 (2.8) 26 (2.2) 48 (4.2) 23 (2.0) Cardiac arrhythmia 32 (2.8) 34 (2.9) 34 (3.0) 36 (3.1) Pleural effusion or empyema 22 (1.9) 27 (2.3) 12 (1.0) 33(2.9) No pathology 22 (1.9) 21 (1.8) 30 (2.6) 20 (1.7) Stable angina pectoris 16 (1.4) 17 (1.5) 13 (1.1) 7 (0.6) Pulmonary embolism 14 (1.2) 18 (1.6) 29 (2.5) 28 (2.4) Lung cancer or pulmonary metastases 8 (0.7) 19 (1.6) 8 (0.7) 21 (1.8) Pericarditis 11 (0.9) 11 (0.9) 9 (0.8) 13 (1.1) ACS with troponin 6 (0.5) 3 ( 0.3) 16 (1.4) 16 (1.4) Interstitial lung disease 6 (0.5) 13 (1.1) 1 (0.1) 6 (0.5) Sinusitis 9 (0.8) 11 (0.9) 9 (0.8) 9 (0.8) Exacerbation CF 7 (0.6) 9 (0.8) 9 (0.8) 10 (0.9) Pneumothorax 7 (0.6) 7 (0.6) 7 (0.6) 6 (0.5)

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