67 Hyperferritinemia in patients with pneumonia Table 1. Baseline characteristics and outcome of patients with CAP stratified according to a plasma ferritin concentration of <500 ng/ml or ≥500 ng/ml Low ferritin (<500ng /ml) Elevated ferritin (≥500ng /ml) P value Patients, n 128 46 Demographics Age, yr, mean (SD) 67.05 (17.39) 66.67 (13.20) 0.895‡ Sex, female, n (%) 68 (53.1) 27 (58.7) 0.632† Body Mass Index, median [IQR] 25.32 [22.70, 28.08] 25.70 [21.40, 29.83] 0.859* Chronic comorbidity, n (%) COPD 41 (32.0) 7 (15.2) 0.046† Asthma 11 (8.6) 2 (4.3) 0.54† Cardiovascular disease1 40 (31.2) 9 (19.6) 0.187† Diabetes 39 (30.5) 11 (23.9) 0.514† Malignancy 35 (27.3) 17 (37.0) 0.301† Hematologic malignancy 10 (7.8) 8 (17.4) 0.122† Solid tumor 26 (20.3) 10 (21.7) >0.99† Neurological disease2 17 (13.3) 1 (2.2) 0.066† Chronic renal disease 14 (10.9) 6 (13.0) 0.909† Immune suppression3 26 (20.3) 18 (39.1) 0.02† Severity of disease on admission PSI, score, median [IQR] 4.0 [3.0, 60.0] 5.0 [4.0, 77.0] 0.039* MEWS, median [IQR] 3.0 [2.0, 5.0] 3.5 [1.25, 5.0] 0.842* qSOFA, score, n (%) 0.712† 0 points 62 (50.8) 19 (44.2) 1 point 55 (44.3) 22 (48.8) 2 points 6 (4.9) 3 (7.0) Hematology Leukocytes ×109, median [IQR] 11.90 [9.35, 14.85] 10.80 [5.30, 15.50] 0.224* Neutrophils ×109, median [IQR] 9.29 [7.13, 12.19] 8.66 [4.99, 15.71] 0.693* Lymphocytes ×109, median [IQR] 1.00 [0.64, 1.43] 1.0 [0.55, 1.83] 0.627* Monocytes ×109, median [IQR] 0.78 [0.60, 1.18] 0.90 [0.36, 1.23] 0.725* Ratio neutrophils : lymphocytes 9.54 [5.88, 14.30] 8.32 [4.74, 18.88] 0.672* Thrombocytes ×109, median [IQR] 233.50 {173.25, 287.00] 205.00 [155.50, 335.50] 0.543* Outcome Length of hospital stay, days, median [IQR] 4.0 [2.25, 7.19] 5.75 [3.0, 11.7] 0.095* ICU admission, n (%) 8 (6.2) 7 (15.2) 0.121† Mortality 28 days, n (%) 6 (4.7) 3 (6.5) 0.925† 4
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