77 Hyperferritinemia in patients with pneumonia Supplementary Table 2. Baseline characteristics and outcome of patients with CAP stratified according to a plasma ferritin concentration of <250 ng/ml or ≥250 ng/ml Low ferritin (<250ng /ml) Elevated ferritin (≥250ng /ml) P value Patients, n 84 90 Demographics Age, yr, mean (SD) 67.07 (18.83) 66.83 (13.75) 0.924‡ Sex, female, n (%) 40 (47.6) 55 (61.1) 0.102† Body Mass Index, median [IQR] 25.54 [22.70, 29.81] 25.12 [22.08, 27.91] 0.42* Chronic comorbidity, n (%) COPD 30 (35.7) 18 (20.0) 0.032† Asthma 7 (8.3) 6 (6.7) 0.897† Cardiovascular disease1 29 (34.5) 20 (22.2) 0.102† Diabetes 24 (28.6) 26 (28.9) >0.99† Malignancy 23 (27.4) 29 (32.2) 0.595† Hematologic malignancy 4 (4.8) 14 (15.6) 0.037† Solid tumor 19 (22.6) 17 (18.9) 0.675† Neurological disease2 12 (14.3) 6 (6.7) 0.162† Chronic renal disease 5 (6.0) 15 (16.7) 0.048† Immune suppression3 13 (15.5) 31 (34.4) 0.007† Severity of disease on admission PSI, score, median [IQR] 4.0 [3.0, 65.25] 4.0 [4.0, 68.0] 0.366* MEWS, median [IQR] 3.0 [2.0, 5.0] 3.5 [1.25, 5.0] 0.842* qSOFA, score, n (%) 0.778† 0 points 42 (51.9) 39 (46.4) 1 point 35 (43.2) 40 (47.6) 2 points 4 (4.9) 5 (6.0) Hematology Leukocytes ×109, median [IQR] 11.80 [9.05, 14.07] 11.85 [7.80, 17.08] 0.652* Neutrophils ×109, median [IQR] 9.18 [7.04, 11.53] 9.20 [6.05, 15.14] 0.66* Lymphocytes ×109, median [IQR] 1.00 [0.69, 1.42] 0.95 [0.57, 1.70] 0.942* Monocytes ×109, median [IQR] 0.80 [0.60, 1.19] 0.77 [0.51, 1.20] 0.519* Ratio neutrophils : lymphocytes 10.43 [5.69, 17.50] 9.08 [5.59, 14.11] 0.529* Thrombocytes ×109, median [IQR] 249.00 [185.25, 295.00] 201.00 [156.00, 273.50] 0.022* Outcome Length of hospital stay, days, median [IQR] 4.0 [2.25, 6.81] 5.25 [3.0, 9.75] 0.051* ICU admission, n (%) 6 (7.1) 9 (10.0) 0.689† Mortality 28 days, n (%) 5 (6.0) 4 (4.4) 0.925† 4
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