102 Chapter 7 Results The study population of this prospective cohort study was composed of 87 EC patients, treated with curatively intended nCRT, dCRT or dRT. Nine more patients were included in this study, and replaced, because of missing or incorrect baseline values (n=6), withdrawal informed consent (n=2) or not meeting the eligibility criteria (n=1). Baseline characteristics and treatment details are presented in Table 1. Table 1 Patient characteristics, treatment characteristics and follow up (n=87) Missing Age(mean) 67.1[87-46] Gender 72 males 15 females Hypertension(medication indicated) 29 (33%) DM 19 (22%) COPD 15 (17%) Smoking current 30 (34%) 1 (1%) Past or current smoker 66 (76%) 1 (1%) Heart attack parents<60 9 (10%) Cardiac history Cardiac any event history 33 (38%) Myocardial infarction (MI) 10 (11%) Coronary ischemia (CI) 18 (21%) Rhythm disorder 11 (13%) Heart failure 1 (1%) Valve disorder 3 (3%) Treatment Chemotherapy 82 (94%) 95% Carbo/Taxol ; 5% 5-FU/Cispl Pathology Adeno 67 SCC 17 Unknown 3 RT dose 44.2 SE 0.57 Mean lung dose (MLD) 8.28 SE 0.31 Mean heart dose (MHD) 19.25 SE 0.75 Surgery performed 51 36 Events during follow up Any new cardiac event* 25 (29%) Myocardial infarction 2 (2%) Coronary ischemia 5 (6%) Rhythm disorder 15 (17%) Pleural effusion 14 (16%) Pericardial effusion 2 (2%)
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