Chapter 4 66 Table 1 Patient characteristics Characteristic Total N = 104 Group A No SDB N=65 Group B Undiagnosed SDB N=39 P-value Demographic data Age, years 59 ± 10 57 ± 9 62 ± 9 0.01 Female sex 34 (33) 15 (23) 19 (49) 0.01 Type of AF Paroxysmal AF 77 (74) 52 (80) 25 (64) 0.07 Nonparoxysmal AF 27 (26) 13 (20) 14 (36) 0.07 LA size LAVI, ml/m2 38 ± 14 36 ± 14 41 ± 14 0.07 Scores CHA2DS2-VASc 1.4 ± 1.3 1.0 ± 1.0 2.1 ± 1.3 <0.001 CHA2DS2-VASc ≥2 44 (42) 18 (28) 26 (67) <0.001 Modifiable risk factors Obesity, BMI ≥30 kg/m2 20 (19) 9 (14) 11 (28) 0.07 BMI 26.5 (24.4-29.2) 25.7 (24.2-28.8) 27.8 (26.4-31.1) 0.02 Diabetes 7 (7) 1 (2) 6 (15) 0.01 Hyperlipidaemia 12 (12) 7 (11) 5 (13) 0.76 Hypertension 42 (40) 15 (23) 27 (69) <0.001 Smoking 6 (6) 3 (5) 3 (8) 0.67 Alcohol use* 9 (9) 3 (5) 6 (15) 0.08 Type of procedure PVI only 96 (92) 60 (92) 36 (92) 1.00 PVI and substrate ablation 8 (8) 5 (8) 3 (8) 1.00 Antiarrhythmic drugs None 34 (33) 28 (43) 6 (15) 0.004 Flecainide 21 (20) 13 (20) 8 (21) 0.95 Betablockers 34 (33) 18 (28) 16 (41) 0.16 Sotalol 25 (24) 12 (19) 13 (33) 0.09 Amiodaron 2 (2) 1 (2) 1 (3) 0.71 Verapamil 4 (4) 2 (3) 2 (5) 0.58 Digoxin 3 (3) 1 (2) 2 (5) 0.28 Data are presented as mean ± SD, median (IQR) or as n (%). AF = atrial fibrillation; AHI = apneahypopnea index; BMI = body mass index, LA = left atrial, LAVI = left atrial volume index, PVI = pulmonary vein isolation, SDB = sleep-disordered breathing. *Alcohol use was defined as >1 standard drink per day.
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