135 Unraveling nitrogen, sulfur and carbon microbial bioreactor responses to stress coastal ecosystems, and should be considered into future modeling efforts that aim to predict coastal ecosystem responses to environmental change. Data Availability Metagenomic trimmed reads, metatranscriptomic trimmed reads, metagenomeassembled genomes and unbinned contigs have been deposited on NCBI under BioProject number PRJNA758578. Author Contributions HJMO, MSMJ, CUW, and PDM planned and designed the study. PDM, MJEM, JMK, AA, and HTO executed the research project. PDM and MJEM wrote the manuscript with input from all co-authors. All authors read and approved the final version submitted. Acknowledgements We thank Dr. Arjan Pol and Dr. Tom Berben for research discussions and suggestions, and Dr. Michiel in ‘t Zandt for data visualization inspiration. We also thank Theo van Alen for in-house sequencing support. Additionally, we are grateful to Prof. Guo-Jun Xie and Dr. Nie for sharing “Ca. Methylomirabilis” genomes with us in busy times. Funding This research was funded by the Soehngen Institute of Anaerobic Microbiology (SIAM) Gravitation Grant 024.002.002, European Research Council Synergy Grant MARIX 854088, and Nederlandse Organisatie voor Wetenschappelijk Onderzoek Grant ALWOP.293. Supplementary Information 4
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