TABLE OF CONTENTS Summary 11 Samenvatting 16 Resumen 20 Laburpena 24 Chapter 1 Introduction and thesis outline 29 Chapter 2 Sulfide toxicity as key control on anaerobic oxidation of methane in eutrophic coastal sediments 43 Chapter 3 Contrasting methane, sulfide, and nitrogen loading regimes in bioreactors shape microbial communities originating from methane-rich coastal sediment of the Stockholm Archipelago 75 Chapter 4 Unraveling nitrogen, sulfur, and carbon metabolic pathways and microbial community transcriptional responses to substrate deprivation and toxicity stresses in a bioreactor mimicking anoxic brackish coastal sediment conditions 103 Chapter 5 Physiological stress response to sulfide exposure of freshwater anaerobic methanotrophic archaea 137 Chapter 6 Osmoregulation in freshwater anaerobic methaneoxidizing archaea under salt stress 165 Chapter 7 Methanotrophic flexibility of “Ca. Methanoperedens” and its interactions with sulfate-reducing bacteria in the sediment of meromictic Lake Cadagno 203 Chapter 8 Synthesis and discussion 231 References 259 Appendices 291 Research data management 292 Acknowledgments | Agradecimientos | Eskerrak 294 Curriculum vitae 300 List of publications 301 Outreach 302
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