Connie Rees

133 Results All results are reported in the format of median (quartiles 1–3). A. Validation in Healthy Volunteers Forty-four TVUS recordings from 11 healthy volunteers during the four different phases of the menstrual cycle were originally planned. However, due to drop-out of some subjects, two during Menses and one during LF, a total number of 41 TVUS recordings were eventually available for the analysis. These recordings underwent a quantitative quality check as introduced in Section II-C. Based on this, five additional recordings (two during Menses, one during EL, and two during LF) were excluded. Therefore, a total of 36 TVUS recordings (seven during Menses, eight during LF, ten during EL, and 11 during LL) were processed and contributed to our statistical analysis. Figure 6A shows the MV in C2F and F2C direction extracted from the four selected phases of a normal menstrual cycle. From Menses to the LF phase, the MV in C2F direction increases from 0.72 (0.48–0.77) to 0.76 (0.63–0.96) mm/s, while it decreases to 0.71 (0.67–0.85) mm/s in the EL phase and 0.50 (0.49–0.61) mm/s in the LL phase. The MV in the F2C direction shows the same trend, with values of 0.66 (0.46–0.74) mm/s during Menses, 0.93 (0.56–1.31) mm/s in the LF phase, 0.75 (0.68–0.88) mm/s in the EL phase, and 0.52 (0.41–0.60) mm/s in the LF phase. In particular, the MV in the C2F direction shows a significant difference between the LF phase and the LL phase (p = 0.0130) and between the EL and the LL phases (p = 0.0473). Instead, the MV in the F2C direction shows a significant difference between the LF and the LL phases (p = 0.0183) and between the EL and the LL phases (p = 0.0205).

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