173 Materials and methods Review protocol: The review protocol is available on PROSPERO under the ID CRD42021244280. Study eligibility criteria The researched population in this review were women with uterine abnormalities such as leiomyomas, adenomyosis, endometriosis and congenital uterine anomalies. Studies were only included if in vivo uteri were studied. Studies were included if uterine peristalsis was investigated in premenopausal women aged over 18 with regular menstrual cycles without hormonal therapy. The patients should not have received any surgical uterine treatment at baseline. Intervention studies, studying the effect of treatment of uterine abnormalities on uterine peristalsis were included if measurement of uterine peristalsis was also done prior to treatment. Cohort studies and casecontrol studies were deemed eligible for inclusion. Data reported in secondary analysis (reviews), case reports, letters to editors, conference abstracts, and protocols for ongoing studies were excluded. Due to the expected scarcity of relevant studies, studies were not excluded based on the method employed for the uterine contraction measurement. Articles were only included if published in English. Data sources Multiple databases were accessed on April 28th, 2022, in the search for relevant literature, namely: PubMed, the Cochrane Library and Embase. The search was repeated on June 17th, 2023, with no new relevant studies found. Search strategy Several key words were selected and included the terms “Uterine Contraction”, “Peristalsis”, “Uterus”, “Uterus/ abnormalities”, “Leiomyoma”, and “Adenomyosis”. Not only MeSH terms, but also free text terms [tiab] were used including “junctional zone contraction”, “endometrial wave”, “subendometrial contraction” and “congenital uterine anomaly”. Snowballing was also used to find further relevant articles. The full literature search including all used key words can be found in Appendix A. Study screening and selection
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