184 prospecti ve study undergoing myomectomy Indication for myomectomy: 7 infertility, 5 dysmenorrhea/ menorrhagia nt with one catheter in the tip of the fundus, 2-4 hours deformatio n index (day 10 – 15) and vasopressin deformation index: increased Yoshino et al. (2010) Controlle d prospecti ve study Leiomyoma s (partially endometrio sis) 51 patient s Solely Intramural leiomyomas, no other infertility factors (except endometriosi s), MRI during implantation window Age 29-41 years, normal menstrual cycles with normal hormones (FSH, LH, prolactin, oestradiol and progesterone), tubal patency, normal BBT cycle. / Cine MRI, 3 min. Presence, frequency, presence of endometrio sis, location and number of leiomyoma s Implantatio n/ luteal phase (day 5-9) Infertility treatment Junctional zone movement 57% low frequency (01x/3 min.) and 43% high frequency (36x/3min.) UP Endometriosis morbidity same in both groups Yoshino et al. (2012) Controlle d prospecti ve study Leiomyoma s 15 patient s Infertility ≥ 24 months with intramural leiomyoma, ≥ 12 months when severe symptoms present, no other infertility factors, MRI before and after myomectomy at luteal day 5-9, high frequency (≥2x/3min.) UP before surgery. Age 29-41 years, normal menstrual cycles with normal hormones (FSH, LH, prolactin, oestradiol and progesterone), tubal patency, normal BBT cycle. / Cine MRI, 3 min. Presence, frequency Luteal phase day 5-9 Myomecto my Junctional zone movement Frequency normalized in 14/15 patients from ≥ 2x/3 min. to 01x/3min. 1 patient from 5x/3min. to 3x/3min. Abbreviations: UFE, uterine fibroid embolisation; UAE, uterine artery embolisation; CF, direction of uterine contractions cervix-to-fundus; UP, uterine peristalsis; rAFS-stage, revised American Fertility Society-stage; HSSG, hysterosalpingoscintigraphy; TVUS, transvaginal ultrasound; VSUP, video sonography of uterine peristalsis; FC, direction of uterine contractions fundus-to-cervix; USgHIFU, Ultrasound-Guided High-Intensify Focused Ultrasound; IUD, intra-uterine device; BBT, basal body temperature.
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