212 Late follicular phase UC features of adenomyosis patients versus healthy controls during the LF phase are presented in Table 8.5. The adenomyosis group shows statistically significantly lower CF in the AW (1.49±0.22 vs. 1.68±0.25, p=0.021), higher amplitude in both AW and PW (0.087±0.042 vs. 0.050±0.018, p=0.001 and 0.076±0.039 vs. 0.046±0.018, p=0.001), lower velocity in both F2C and C2F directions of the AW (0.65±0.18 vs 0.88±0.29, p=014 and 0.64±0.18 vs. 0.84±0.22, p=0.020, respectively) and F2C direction of the PW (0.64±0.20 vs. 0.82±0.21, p=0.014), and reduced contraction coordination (0.34±0.08 vs. 0.26±0.17, p=0.015) compared to healthy controls. Table 8.5. UC features in adenomyosis patients and healthy controls during the LF phase of the menstrual cycle UC feature Direction of UC feature Adenomyosis patients (n=10) Healthy controls (n=48) P-value* CF (contractions/minute) AW in radial direction 1.49 (0.22) 1.68 (0.25) 0.0212 PW in radial direction 1.60 (0.29) 1.72 (0.27) 0.2221 Amplitude (SD) AW in radial direction 0.087 (0.042) 0.050 (0.018) 0.0012 PW in radial direction 0.076 (0.039) 0.046 (0.018) 0.0012 Velocity (mm/s) F2C propagation, AW 0.65 (0.18) 0.88 (0.29) 0.0142 C2F propagation, AW 0.64 (0.18) 0.84 (0.22) 0.0202 F2C propagation, PW 0.64 (0.20) 0.82 (0.21) 0.0142 C2F propagation, PW 0.77 (0.30) 0.90 (0.20) 0.1282 Coordination (MSE) 0.34 (0.08) 0.26 (0.17) 0.0152 All data are presented as mean (SD). *p-value was considered significant at <0.05. UC: uterine contractions; CF: contraction frequency; AW: anterior wall; PW: posterior wall; F2C; fundus-to-cervix; C2F: cervix-to-fundus 1T-test for independent samples 2 Mann-Whitney test
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