235 Matching Matching of the study group(s) based on age during IVF/ICSI, number of embryos transferred and type of subfertility (primary or secondary) was performed separately for each study subgroup. This resulted in 33 adenomyosis patients matched to 53 controls, with three unmatched patients in the adenomyosis group and one patient with only one match. For the endometriosis only group, 60 patients were matched to 118 controls, with one unmatched patient. In the combined group, 85 patients were matched to 164 controls, with eight unmatched patients. In total, 178 adenomyosis/endometriosis patients were matched to 354 male infertility controls. The resulting separate control groups had comparable characteristics, allowing for differences across the matching variables (see Appendix C). Matching based on embryo quality was not possible, due to the low number of exact matches (55 unmatched subjects). IVF/ICSI outcomes after matching IVF/ICSI outcomes after matching were compared between the different adenomyosis/endometriosis subgroups and the control group (see Table 9.3). Compared to their matched controls, the biochemical pregnancy rate was 33.3% for the adenomyosis group, 28.8% for the endometriosis group and 21.2% for the combined group. The ongoing pregnancy rate was 28.1% in the adenomyosis group, 25.4% in the endometriosis group and 12.9% in the combined group. Miscarriage rate (as the difference between biochemical and ongoing pregnancy, see Table 9.3) was not significantly different between groups. The live birth rate was 25% for both the adenomyosis and endometriosis group and was 11.9% in the combined group. Only the outcomes of the combined group differed significantly from their matched controls (p<0.01).
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