254 Table 10.2 Patient Characteristics of IVF/ICSI Patients with MRI-Diagnosed Adenomyosis versus Male Infertility Controls Adenomyosis (N=124) Control Group (N=889) P-value BMI in kg/m2 (Median, IQR) 23.95 (21.30-28.33) 23.60 (21.44-27.04) 0.48 Infertility time in months (Median, IQR) 35.00 (23.50-53.50) 27.00 (20.00-41.00) 0.11 Age during 1st IVF cycle (Years, Median, IQR) 33.00 (30.00-35.50) 31.00 (28.00-35.00) 0.042 Year of IVF Treatment (Median, (IQR)) 2011 (2008-2016) 2011 (2009-2014) 0.54 Cycle length (Days, Median, IQR) 28.00 (28.00-30.00) 28.00 (28.00-30.00) 0.43 Primary subfertility 79 (63.7%) 616 (69.4%) 0.92 Secondary subfertility 36 (29.0%) 272 (30.6%) Indication for fertility treatment - Male Factor - Female Factor§ - Combined - Endometriosis - Idiopathic 20 (16.3%) 13 (10.6%) 26 (21.1%) 37 (30.1%) 27 (22.0%) 889 (100%) <0.001 Type of treatment (N, (%)) - IVF - ICSI 93 (75.0) 31 (25.0) 177 (19.9) 712 (80.1) <0.001 Number of viable oocytes (Median, IQR) 7.0 (4.0-10.0) 8.0 (5.0-12.0) 0.015 Number of viable embryos (Median, IQR) 4.0 (2.0-6.0) 5.0 (3.0-8.0) <0.001 Fertilisation rate (%, Median, IQR) 60.0 (45.0-75.0) 57.1 (40.0-72.0) 0.21 Number of Embryos Transferred (N, (%)) - Single - Double 83 (68.0) 39 (32.0) 570 (64.2) 318 (35.8) 0.42 Embryo quality of First Transferred Embryo (N, (%)) a - Super - Good - Fair - Moderate - Poor 28 (23.5) 19 (16.0) 48 (40.3)* 22 (18.5) 2 (1.7) 298 (33.7) 138 (15.6) 314 (50.6) 133 (14.9) 33 (3.7) 0.11 Embryo quality of Second Transferred Embryo (N, (%)) a - Super - Good - Fair - Moderate - Poor 2 (5.7)* 8 (22.9) 19 (54.3) 5 (14.3)* 1 (2.9)* 0 (0.0) 63 (20.1) 217 (69.1) 0 (0.0) 34 (10.8) <0.001 *an asterisk denotes statistically significant difference versus control. a: see Table 9.S3 for details on embryo quality criteria. § Female factor infertility included indications such as: ovulation disorders, tubal factor and cervical issues as IVF/ICSI indications. Controls more often underwent ICSI treatment (80.1% vs. 25.0%, p<0.001) and also had more viable oocytes (8.0 vs. 7.0, p=0.015) and embryos (5.0 vs. 4.0, p<0.001) versus adenomyosis patients. Embryo quality was similar between groups (p=0.112), but did differ (p<0.001) when looking only at the second transferred embryo where applicable.
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