274 appropriate to account for multiple comparisons and repeated measures. A pvalue of <0.05 was considered as statistically significant for all variables. This study is reported according to the STROBE guidelines (189) (see Appendix 11G for the STROBE checklist). Figures were created using Miro and SPSS. Ethical Considerations: No informed consent was requested from the patients included as only anonymized data that is already publicly available was used. For the correlation between databases, a TTP was used de-anonymize and link the databases. Ethical approval from the regional ethical committee was obtained with local study number nWMO-2020.0015.
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