Connie Rees

277 History of HDP +0.1% P=0.444 Hyperemesis gravidarum +0.3% P<0.001 IVF: In-vitro Fertilization, ICSI: Intracytoplasmic sperm injection; HDP: Hypertensive disorders of Pregnancy, PIH: Pregnancy-Induced Hypertension *P-value calculated using Chi2 analysis for dichotomous outcomes, Independent T-test for normally distributed continuous variables and Mann-Whitney U test for abnormally distributed continuous variables. **Some outcomes are reported only as a relative percentage difference between patient groups instead of absolute values, due to CBS data privacy restrictions. In some cases, this leads to percentages not adding up to 100%. Obstetric characteristics were compared between groups (Table 11.1). Several significant differences were found between the adenomyosis patient pregnancies and those of the general Dutch population. Women with histopathological adenomyosis were more often primiparous (65.8% vs. 55.0%), and had more reported subfertility (+4.7%) and subsequently were more often pregnant after undergoing ART. Table 11.2 shows descriptive analysis of all obstetric and maternal outcomes. Multivariate binary logistic regression analysis was performed for obstetric and neonatal outcomes. All outcomes were corrected for potential confounders: parity, age, year of birth, multiple gestation, induction of labour, low-income area, ethnicity, gestational diabetes, history of hypertensive disorder. Univariate analysis for relevant outcomes can be found in Table 11.S6. Table 11.S7 shows the full outcomes of multivariate regression analysis.

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