vi Table 2.S3 Empty Diagnostic Accuracy Parameters Table Article Sensitivity (%) Specificity (%) NPV (%) PPV (%) Author, Year Table 2.S4 Data Extracted for Studies not investigating Diagnostic Accuracy Studies not investigating Diagnostic Accuracy Authors, year Study design e.g. retrospective/prospective cohort, pilot, feasibility, interventional, observational Study objective e.g. diagnostic accuracy, treatment evaluation, differentiating adenomyosis vs fibroids Study population (N) Study inclusion criteria e.g. symptomatic women receiving surgery Study exclusion criteria e.g. using hormonal therapy, post-menopausal Comparison groups e.g. with adenomyosis vs. without adenomyosis (if applicable) (MRI vs. TVUS etc.) Adenomyosis definition used e.g. JZ >12mm on MRI, histopathological diagnosis, TVUS MUSA criteria, clinical symptoms MRI slice thickness (mm) e.g. 3mm, 4mm MRI systems used e.g. 1.5T, 3T MRI sequences/techniques/settings used e.g. T1/T2/DWI/DTI/T1-contrast-enhanced All MRI features investigated Signal intensity, JZ irregularity, JZ thickness etc. Objectified MRI features JZ thickness, JZ diff, JZ-Myometrium ratio etc., Apparent Diffusion Coefficient Outcomes measured e.g. Symptom severity, menstrual blood volume, pain, change in uterine volume Results of Adenomyosis characteristics on MRI e.g. mean JZ thickness, mean uterine volume, # diffuse cases, # focal cases, Adenomyosis-related Results E.g. correlation with symptom reduction y/n, reduction in JZ thickness, degree of uterine volume reduction, diagnostic accuracy/specificity/sensitivity Comments
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