cxvi events as consequen ce of interventio n reported 9 Characteri stics of patients lost to follow-up described 1 N/ A 0 1 N/ A 1 N/ A 0 N/ A N/ A 0 N/ A N/ A 1 1 0 1 1 0 Exact probability values reported for main outcomes 1 0 0 1 1 0 0 1 0 N/ A N/ A N/ A 0 0 1 0 1 External validity 1 1 Subjects asked to participate were representa tive of source population 1 UT D 0 UT D UT D UT D UT D UT D UT D 1 UT D UT D UT D UT D UT D 1 UT D 1 2 Subjects prepared to participate were representa tive of source population 1 0 1 1 UT D 0 0 UT D UT D 1 UT D UT D UT D UT D UT D UT D UT D 1 3 Location of study interventio n was representa tive of source population 1 N/ A 1 0 N/ A 1 N/ A N/ A N/ A N/ A N/ A N/ A N/ A UT D 1 1 1 Internal validity – bias 1 4 Study participant s blinded to interventio n 1 N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A
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