Connie Rees

cxvii 1 5 Blinded outcome assessment 1 N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A 1 6 Data dredging clearly described, if any 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 7 Analyses adjust for differing lengths of follow-up 1 N/ A N/ A 1 N/ A 0 N/ A N/ A N/ A N/ A 1 N/ A N/ A 0 1 0 0 1 8 Appropria te statistical tests used 1 1 1 1 1 1 1 UT D 1 N/ A N/ A N/ A 1 1 UT D 1 UT D 1 9 Complianc e with interventio ns was reliable 1 N/ A 1 1 N/ A 1 N/ A N/ A N/ A N/ A 1 N/ A N/ A 1 1 1 1 2 0 Outcome measures were used accurate 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 Internal validity - confounding (selection bias) 2 1 All participant s recruited from the same source population 1 1 1 N/ A 0 N/ A 0 UT D UT D 1 UT D 0 1 N/ A N/ A 1 N/ A 2 2 All participant s recruited over the same time period 1 UT D UT D N/ A 0 N/ A UT D UT D UT D 1 UT D UT D 1 N/ A N/ A 1 N/ A 2 3 Participant s randomzie d to interventio n(s) 1 N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A 2 4 Allocation of interventio n concealed from 1 N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A N/ A

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