Connie Rees

cxxviii Criteria for choice of Fresh ET Embryo: - For ET, the embryos of the highest available quality are chosen. - Super > Good > Fair > Moderate > Poor - When multiple embryos of equal final quality are available, the choice depends on how the embryo(s) were on day 2,. Whereby: 4 cell > 2 cell > 3 cell - IN the case of continued division from day 2 to day 3, priority is given to the embryo that is dividing ‘on schedule’. - In the case of fragmentation, concentrated pockets of fragmentation are preferred to diffuse fragmentation - If there are no embryo dividing ‘on schedule’ preference is given to embryos with higher uniformity - 2pna > 2pnb > 0pn > 1pn - Embryos >24 hours behind the expected stage of development are not eligible for ET. In the case of stagnation between days 2 and 3 (without deterioration in quality), ET is potentially possible. 10D: Sub-analysis of IVF/ICSI Outcomes Table 10.S4: Sub-analysis for Adenomyosis patients with and without pregnancies after IVF/ICSI based on MRI-timing *chi-squared analysis Pregnancy (N=31) No Pregnancy (N=93) P-value* MRI prior to IVF/ICSI treatment Yes 12 (38.7%) 34 (36.6%) 0.830 No 19 (61.3%) 59 (63.4%) MRI within 5 years of fertility treatment Yes 21 (67.7%) 62 (66.7%) 0.912 No 10 (32.3%) 31 (33.3%)

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