Connie Rees

cxxx Live Birth 5 (16.7%) 12 (13.3%)a 233 (26.8%) 0.055 Diffuse Adenomyosis (N=31) Focal Adenomyosis (N=58) Control Group (n=889) Biochemical Pregnancy 10 (32.3%) 12 (20.7%) 323 (36.3%) 0.117 Ongoing Pregnancy 5 (17.2%) 9 (15.5%) 261 (29.4%) 0.047 Live Birth 5 (16.7%) 9 (15.5%) 233 (26.8%) 0.446 Adenomyosis Alone (n=31) Adenomyosis and Endometriosis (n=93) Control Group (n=889) Biochemical Pregnancy 9 (29.0%) 22 (23.7%) 323 (36.3%) 0.040 Ongoing Pregnancy 6 (20.0%) 12 (14.1%) 261 (29.4%) 0.005 Live Birth 5 (17.2%) 12 (14.1%) 233 (26.8%) 0.049 Adenomyosis without DIE (n=98) Adenomyosis with DIE (n=26) Control Group (n=889) Biochemical Pregnancy 27 (27.6%) 4 (15.4%) 323 (36.3%) 0.024 Ongoing Pregnancy 17 (17.7%)a 2 (7.7%)a 261 (29.4%) 0.004 Live Birth 15 (15.8%) 2 (7.7%) 233 (26.8%) 0.039 *Chi-squared analysis with Bonferroni correction. a: denotes statistical significance vs. control group Table10. S7: Adjusted Odds Ratio IVF/ICSI Outcomes versus Controls IVF/ICSI Outcome Adjusted Odds Ratio (95% CI) vs Control Group* Adenomyosis Patients Overall (N=124) Biochemical Pregnancy 0.683 (0.411-1.138) Ongoing Pregnancy 0.501 (0.276-0.909) Live Birth 0.484 (0.259-0.905) Adenomyosis Patients without Myometrial Cysts (N=63) Adenomyosis Patients with Myometrial Cysts (N=60) Biochemical Pregnancy 0.612 (0.314-1.195) 0.708 (0.367-1.365) Ongoing Pregnancy 0.513 (0.237-1.112) 0.500 (0.229-1.090) Live Birth 0.556 (0.255-1.214) 0.420 (0.177-0.997) Adenomyosis Patients with Mean JZ<12mm (N= 103) Adenomyosis Patients with Mean JZ>12mm (N= 20) Biochemical Pregnancy 0.746 (0.436-1.270) 0.407 (0.113-1.465) Ongoing Pregnancy 0.531 (0.285-0.990) 0.363(0.079-2.659)

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