Connie Rees

53 Table 2.1: Objective Measures of Adenomyosis on MRI MRI Feature Definition Unit Possible Stratification Studies Mentioned (N)* Junctional Zone Parameters Mean JZ Average Junctional Zone diameter Mm <5mm, <7mm, <8mm, <10mm, <12mm >12mm, >15mm N=56 (4,8,45,51– 53,59,60,77,100,113,116– 118,120,122–162) JZ Max Maximal diameter of Junctional Zone Mm <7mm, <10mm, <12mm >12mm, >15mm N=18 (4,8,45,51– 53,59,60,77,100,113,116– 118,120,122–162) JZ Min Minimal diameter of Junctional Zone Mm N=5 (4,122,123,149) JZ Diff As a measure of JZ irregularity Difference between maximal and minimal JZ Mm <5mm difference and >5mm difference N=7 (4,45,122,123,149,155,159) JZ Asymmetry Difference between anterior and posterior Junctional Zone Mm <2mm difference >2mm difference N=1 (137) Junctional Zone to Myometrium Ratio Ratio of Junctional zone to full myometrium thickness at the same point of the uterine wall At maximal JZ, or as an average % >40% and <40% N=16 (4,12,45,52,72,123,125,128, 131,136,144,146,149,151,1 55,160) Adenomyosis lesion size Adenomyotic foci volume Volume of adenomyotic foci in 3 orientations Mm3 Diameter <40mm 40-60 mm >60mm N=27 (4,12,49,52,118,121,122,12 6,131,133– 135,140,141,151,154,158,1 62–168). Uterine Parameters Uterine Volume Uterine volume measured at midcorpus in 3 orientations Mm3 N=28 (4,53,60,121,122,130,133,1 36–138,142,144– 146,150,153,155,156,159,1 63,164,166–171) Uterine Length Measured from cervix to fundus in sagittal orientation Mm N=7 (23,29,32,57,71,78,80,89) Average Uterine Wall Thickness Uterine wall thickness measured from endometrium to myometrium Mm N=12 (8,51,151,160,77,100,136– 138,143,148,149). Uterine Asymmetry Difference between anterior and posterior uterine wall Mm N=4 (8,113,137,149) Tissue Signal Intensity Number of high signal intensity adenomyotic foci Absolute number of visible high signal intensity myometrial foci (compared to normal myometrium) on T1 or T2 imaging n N=3 (49,126,163)

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