Connie Rees

81 Diagnostic accuracy Table 3.3 presents the diagnostic accuracy of MRI in general and the individual potential predictors of adenomyosis. MRI overall had a sensitivity of 50.4%, a specificity of 66.9%, a PPV of 55.9%, a NPV of 61.8%, a positive LR of 1.5, and a negative LR of 0.7. The overall accuracy was 59.4%. A history of curettage showed an overall accuracy of 59.7%, with a sensitivity of 22.1%, a specificity of 91.1%, a PPV of 67.4%, a NPV 58.4%, a positive LR 2.5, and a NLR of 0.9. Additionally, AUB had a sensitivity of 94.2%, a specificity of 11.1%, a PPV of 47.9%, and a NPV of 68.8%. The positive LR of AUB was 1.1, negative LR 0.5, and overall accuracy 49.7%. A JZ Diff ³ 5 mm on MRI had an overall accuracy of 54.8%, with a sensitivity of 88.6%, a specificity of 22.0%, a PPV of 52.5%, a NPV of 66.7%, a positive LR of 1.1, and a negative LR of 0.5. The sensitivity of the presence of HSI foci was 40.3%, the specificity was 91.0%, the PPV was 48.4%, and the NPV was 52.6%. The positive LR was 4.8, the negative LR was 0.7, and the overall accuracy was 68.1%. Reader (CR and MvdW) detection versus initial radiologist diagnosis is shown in Table S3. In tests for individual prognostic diagnostic potential using the ROC-curve, no continuous variables showed an AUC ³0.7. Highest AUCs were found for mean JZ thickness and JZ Max (AUC .624) (data not shown).

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