82 Table 3.3: Diagnostic Accuracy of MRI and Clinical Parameters for Histopathological Adenomyosis Diagnosis Histopathological Adenomyosis Diagnosis Sensitivity Specificity PPV NPV PLR NLR Overall accuracy MRI Overall 50.4% 66.9% 55.9% 61.8% 1.5 0.7 59.4% Intoxications Smoking 38.9% 57.7% 44.3% 52.2% 0.9 1.1 49.0% Medical History History of Curettage 22.1% 91.1% 67.4% 58.4% 2.5 0.9 59.7% History of Caesarean Section 91.7% 5.2% 37.5% 50.0% 0.9 1.6 70.2% Irregular cycle 36.1% 59.6% 45.5% 50.0% 0.9 1.1 48.3% Hormonal medication 53.3% 51.9% 47.9% 57.3% 1.1 0.9 52.5% Symptoms Dysmenorrhoea 94.1% 8.3% 49.2% 60.0% 1.0 0.7 50.0% AUB 94.2% 11.1% 47.9% 68.8% 1.1 0.5 49.7% Chronic Pain 97.9% 2.7% 46.3% 60.0% 1.0 0.8 46.7% Subfertility 19.8% 75.2% 40.0% 5.9% 0.8 1.1 50.0% Dyschezia 23.4% 67.4% 37.5% 51.2% 0.7 1.1 47.3% Dyspareunia 72.5% 26.7% 43.1% 55.8% 1.0 1.0 46.5% Endometriosis 53.4% 54.1% 49.3% 50.7% 1.2 0.9 53.8% Uterine Fibroids 34.4% 58.6% 40.9% 51.7% 0.8 1.1 47.6% MRI Features Mean JZmax ³12mm 71.9% 45.5% 54.4% 64.2% 1.3 0.6 58.0% Mean JZdiff ³5 mm 88.6% 22.0% 52.4% 66.7% 1.1 0.5 54.8% Mean JZ/MYO ³.4 71.3% 29.5% 48.4% 52.6% 1.0 1.0 49.6% HSI Foci 40.3% 91.0% 78.8% 64.8% 4.8 0.7 68.1% PPV = Positive Predictive Value; NPV = Negative Predictive Value; PLR = Positive Likelihood Ratio; NLR = Negative Likelihood Ratio; AUB=Abnormal Uterine Bleeding; JZmax = Maximal Junctional Zone Thickness; JZdiff = Junctional Zone Differential; JZ/MYO = Junctional Zone to Myometrium Ratio; HSI = High Signal Intensity.
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