Connie Rees

Part I Summary and introduction 11
Summary 13
Nederlandse Samenvatting 16
Chapter 1 Introduction and thesis outline 19
Part II Diagnosis of Adenomyosis on MRI 39
Chapter 2 Objective measures of Adenomyosis on MRI and their Diagnostic Accuracy: a systematic review and meta analysis 41
Chapter 3 Prediction of Adenomyosis Diagnosis based on MRI 69
Chapter 4 Prediction of Adenomyosis Diagnosis based on MRI: an external validation study 91
Part III Effect of Adenomyosis on Uterine Contractile Function 113
Chapter 5 Quantitative ultrasound imaging and characterisation of uterine peristaltic waves 115
Chapter 6 Normal uterine contractile activity in healthy women throughout the menstrual cycle: an exploration of reference values using a novel quantitative 2D TVUS speckle tracking method 149
Chapter 7 The influence of uterine abnormalities on uterine peristalsis in the non-pregnant uterus: a systematic review 169
Chapter 8 Quantitative Ultrasound Measurement of Uterine Contractility in Adenomyotic versus Normal Uteri : A Multi-centre Prospective study 195
Part IV Effect of Adenomyosis on Fertility Outcomes 219
Chapter 9 Women with combined adenomyosis and endometriosis on MRI have worse IVF/ICSI outcomes adenomyosis and endometriosis alone: A matched retrospective cohort study compared to 221
Chapter 10 MRI Markers of Adenomyosis Severity Associated with Worse IVF/ICSI Outcomes 243
Part V Effect of Adenomyosis on Obstetric Outcomes 264
Chapter 11 The ADENO study: ADenomyosis and its Effect on Neonatal and Obstetric outcomes: a retrospective population-based study 267
Part VI Discussion 291
Chapter 12 General discussion and future perspectives References 293
Part VII Supplementary Material 339
Appendices per Chapter 341
List of Author’s Publications 342
Conference Abstracts and Presentations 344
Acknowledgements 356
Curriculum Vitae 366

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