14800-DvRappard

14 Chapter 1 Figure 2 . Macrophages are red with the toluidine blue stain indicating that they contain sulfatides; metachromasia. Figure 3 . (A) Large, foamy macrophages containing metachromatic granules. (B) shows the storage of sulfatides in astrocytes. In (C) the sulfatide storage in neurons is visible. The sulfatide storage also affects axon density and neurons (Figure 3B,C). 13 Fibrous gliosis arises in the extracellular spaces of the demyelinated cerebral white matter as a result of astrocyte proliferation. 14 These astrocytes contain metachromatic granules.