14800-DvRappard

92 Chapter 6 Figure 1. MLDat a glance. (A) shows the biochemical reaction impaired inMLD, the desulfation of 3-0-sulfogalactosyl glycolipids (“sulfatides”) to galactosylceramide. (B) T2-weighted MRIs demonstrating the improvement of brain white matter abnormalities in a successfully transplanted patient, compared with patient 1 whose HCT was not successful. (C) illustrates the effect of HCT in MLD as interpreted so far.