14800-DvRappard

99 Donor macrophages and remyelination in metachromatic leukodystrophy 6 point to additional beneficial effects of HCT beyond cross-correction of enzyme deficiency that could be further exploited in order to improve outcome, probably not only for MLD, but also for other leukodystrophies treated with HCT (e.g. Krabbe disease) and acquired white matter disorders as multiple sclerosis.