Eva van Grinsven

20 Supplementary materials Supplementary Table 4. Cognitive test scores showing the group mean Z-scores for all neurocognitive (sub)tests and overall neurocognitive domain scores. (continued) Cognitive test or domain Mean Z score (SD) Range STROOP - Reading (n = 53)a -0.38 (1.12) -3.00 - 1.00 Psychomotor speed (n = 56)a -1.45 (2.59) -17.70 – 0.71 GP - Dominant hand (n = 55)a -1.59 (3.09) -18.99 - 1.21 GP - Non-dominant hand (n = 55)a -1.28 (2.43) -15.35 - 1.40 Visuospatial functioning (n = 57)a 0.61 (0.68) -1.83 - 1.60 ROCFT - Direct Copy (n = 56)a 0.17 (1.14) -4.18 - 1.24 HVOT – Fragmented (n = 57)a 1.03 (0.62) -1.23 - 2.03 FEEST total (n = 34) -0.95 (1.10) -3.71 - 1.26 Bold values indicate scores that significantly differed from the normative population (i.e. Z = 0), with positive values indicating better and negative values indicating worse performance. Corrected p-value < .0025 for individual (sub)tests and corrected p-value < .008 for overall neurocognitive domain scores. a indicates domain or test-scores which were not-normally distributed and thus assessed using Wilcoxon signed-rank tests. All other measures were tested using one-sample t-tests. Abbreviations: DS, digit span; FEEST, Facial Expressions of Emotion – Stimuli and Tests; GP, Grooved Pegboard; HVLT-R, Hopkins Verbal Learning Test – Revised; HVOT, Hooper Visual Organization Test; ROCFT, Rey Osterieth Complex Figure Test; TMT, trail making test; VAT, Visual Association Test. Subjective and objective neurocognitive functioning Chi-square tests indicated the presence of subjective complaints regarding a cognitive domain did not discriminate between patients with and without objective impairments in that same domain. However, more patients with an attention impairment reported emotional complaints during the semi-structured interview (44%) compared to patients without an attention impairment (15%; p=.037, φ=.276). Additionally, subjective language complaints were more frequently reported by patients with a social cognition impairment (50%) compared to patients without a social cognition impairment (13%; p=.036, φ=.411). When evaluating change in subjective cognitive performance using the continuous VAS difference score, a Mann-Whitney U test indicated patients with visuospatial impairments reported a larger decline in perception from premorbid functioning on the VAS (M=-34.4, SD=32.9) than those without visuospatial impairments (M=-10.4, SD=18.5, p=.045). No differences were found between patients with or without cognitive impairments and VAS difference scores for any of the other tested cognitive domains. As psychomotor performance could be influenced by sensory and/or motor problems additional analyses were performed. Patients with sensory problems were A

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