Eva van Grinsven

67 Appendices ADDITIONAL BASELINE PHYSIOLOGICAL COMPARISON Supplementary Figure 3. Violin plots displaying the differences in OEF, CBF, CMRO2 and CVR values across different tissue types. Asterisks indicate significant differences. Corrected p-value = .017. Abbreviations: Brain metastases, brain metastases; CBF, cerebral blood flow; cGM, cortical grey matter; CMRO2, cerebral metabolic rate of oxygen; CVR, cerebrovascular reactivity; ED, edema; OEF, oxygen extraction fraction; WM, white matter.

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