68 Supplementary materials VOXELWISE DOSE CORRELATIONS Supplementary Figure 4. Voxelwise correlation values for the association between delivered dose and post-radiotherapy change in OEF, CBF, CMRO2 and CVR in healthy appearing brain tissue. Left column shows box-plots of the correlation values. P-values of the one-sided Wilcoxon signed-rank test are shown in the upper corner. Left column shows the correlation values for each individual patient. Abbreviations: CBF, cerebral blood flow; CMRO2, cerebral metabolic rate of oxygen; CVR, cerebrovascular reactivity; OEF, oxygen extraction fraction. A
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