Anne Fleur Kortekaas-Rijlaarsdam

43 MPH AND ACADEMIC PERFORMANCE: META-ANALYSIS 2 Author, year N Mean age (SD) Design Titration on academic outcome? Relevant academic measures Academic tasks Mediators and moderators Included in meta-analysis If not: reason and results (Wigal et al., 2011) 71 10.1 (1.1) Within subject design comparing placebo to clinically titrated dosage (avg. dose 25.5 mg.) No Math accuracy Math productivity PERMP 2,3,4,5,8,9,10,11,12,13 Yes (Schulz et al., 2010) 139 10.2 (1.8) Within subject design comparing placebo to one fixed dose (20 mg.) No Math accuracy Math productivity PERMP 3,4,5,8,9,10,11,12 Yes (Bental & Tirosh, 2008) 25 9.2 (1.0) Within subject design comparing placebo to one fixed dose (0.3-0.4 mg/kg) No Spelling accuracy Spelling list No: insufficient studies for meta-analysis Results: MPH did not improve spelling accuracy (Muniz et al., 2008) 81 9.5 (1.7) Within subject design comparing placebo to two fixed doses (36 and 54 mg.) Yes, 54 mg. most effective for math correct and math attempted Math items correct Math number attempted PERMP No exact values not available Results: MPH improved (1) number of math items completed correctly and (2) math number attempted (Rubinsten, Bedard, & Tannock, 2008) 18 9.7 (1.2) Within subject design comparing placebo to three fixed doses (10, 15 and 20 mg.) Yes, 20 mg. most effective for math accuracy Math accuracy RAS math No exact values not available Results: MPH improved math accuracy (Wilens et al., 2008) 115 8.8 (2.2) Within subject design comparing placebo to clinically titrated dosage (avg. dose 20.3 mg.) No Math accuracy Math productivity PERMP 2,3,4,8,9,11,13 Yes (Gorman, Klorman, Thatcher, & Borgstedt, 2006) 39 9.1 (2.0) Within subject design comparing placebo to one fixed dose (0.4 mg/kg) No Math accuracy RAS math 1,2,3,4,5,6,8,9,10,12,13,14 Yes, in addition to academic improvements on-task behavior improved with 11.4% with MPH compared to placebo (McGough et al., 2006) 79 9.1 (1.7) Within subject design comparing placebo to clinically titrated dosage (avg. dose unknown) No Math accuracy Math productivity PERMP 2,3,4,5,7,8,9,12,13 Yes Supplementary material Table E2.1 Continued