Anne Fleur Kortekaas-Rijlaarsdam

47 MPH AND ACADEMIC PERFORMANCE: META-ANALYSIS 2 Author, year N Mean age (SD) Design Titration on academic outcome? Relevant academic measures Academic tasks Mediators and moderators Included in meta-analysis If not: reason and results (Pelham Jr. et al., 1987) 13 8.8 (1.5) Within subject design comparing placebo to one fixed dose (20 mg) No Math accuracy Reading accuracy Reading number attempted Mad Minute, Barnell Loft 1,2,3,4,5,6,7,8,12,13,14 Yes, with MPH compared to placebo on-task behavior increased with 4.2% (Douglas et al., 1986) 16 9.2 (1.7) Within subject design comparing placebo to one fixed dose (0.3 mg/kg) No Math accuracy Spelling accuracy Math sheet Spelling list 3,4,5,8,9,10,12 Yes for math accuracy, not for spelling accuracy (insufficient studies for meta-analysis) Results: MPH did not improve spelling accuracy but did improve on-task behavior with 4.2% (Pelham, Bender, & Caddell, 1985) 29 8.4 (n.a.) Within subject design comparing placebo to one fixed dose (0.6 mg/kg) No Reading accuracy Spelling accuracy Barnell Loft Spelling list 1,3,4,5,6,8,9,10,12 Yes for reading accuracy, not for spelling accuracy (insufficient studies for meta-analysis) Results: MPH improved spelling accuracy and improved on-task behavior with 12.0% Note. ADHD Attention-Deficit Hyperactivity Disorder; PLA placebo; MPH methylphenidate; PERMP Permanent Product Measure of Performance; SAT Speeded Arithmetic Task; RAS Restricted Academic Situation 1 On-task (mediator); 2 teacher-rated symptom improvements (mediator); moderators: 3 age, 4 %male, 5 %children with ADHD-Inattentive subtype, 6 %children with comorbid Oppositional Defiant Disorder or Conduct Disorder, 7 %children with comorbid Learning Disorder, 8 methylphenidate release system, 9 study duration, 10 time of measurement, 11 dosage, 12 titration method, 13 parent-rated ADHD severity, 14 teacher- rated ADHD-severity; **between-subject study. Supplementary material Table E2.1 Continued