Anne Fleur Kortekaas-Rijlaarsdam

CHAPTER 2 52 Authors (year) I. Cross-over design suitable? II. Biased from carry-over effects? III. First period data available (if relevant, see II) IV. Correct (paired) analysis? V. Comparable with results from parallel trials? VI. Order of treatments randomized? VII. Drop-out reported? Overall score* (Pelham Jr. et al., 1989) Yes Not reported Not reported Yes Not reported Yes Not reported 3 (Barkley, Fischer, Newby, & Breen, 1988) Yes Not reported Not reported Yes Not reported Yes Not reported 3 (Douglas et al., 1988) Yes Not reported Not reported Yes Not reported Yes Not reported 3 (Pelham Jr. et al., 1987) Yes Not reported Not reported Yes Not reported Yes Yes 4 (Douglas et al., 1986) Yes No, drug order included in analysis Irrelevant Yes Yes Yes Yes 5 (Pelham, Bender, & Caddell, 1985) Yes Not reported Not reported Yes Not reported Yes Not reported 3 Note. Scoring was based on criteria I (yes = 1, no = 0), II (no = 1, yes, but first period data available = 1, no/not reported = 0), IV, VI and VII (yes = 1, no/not reported = 0), resulting in a maximum score of 5 (reflecting minimal risk of bias) and a minimal score of 0. Supplementary material Table E2.3 Continued