15502-m-pleumeekers

List of abbreviations AC Articular cartilage/chondrocytes ACAN Aggrecan AFM Atomic force microscopy ALP Alkaline phosphatase AMSC Adipose-tissue-derived mesenchymal stem cell ATMP Advanced therapy medicinal product ATR-FTIR Attenuated total reflectance fourier transform infrared B2M Beta-2-microglobulin BMP Bone morphogenetic protein BMSC Bone-marrow-derived mesenchymal stem cell BNC Bacterial nanocellulose BSA Bovine serum albumin COL1A1 Collagen type I COL2A1 Collagen type II COL10 Collagen type X DC Decellularization DMMB Dimethylmethylene blue E* Young´s modulus EDTA Ethylene diamintetraacetate Ein Instantaneous modulus Eeq Equilibrium modulus EC Ear cartilage/chondrocytes ECM Extracellular matrix EMA European medicines agency EMIMAc 1-Ethyl-3-methylimidazolium acetate FCS Fetal calf serum FDA Food and drug administration sGAG sulfated-Glycosaminoglycan GAPDH Glyceraldehyde 3-phosphate dehydrogenase GMP Good manufacturing practices H Thickness HCT/P Human cells and tissues and cellular- and tissue-based product H&E Haematoxylin and eosin HG-DMEM High glucose Dulbecco's modified Eagle's medium HPRT1 Hypoxanthine phosphoribosyltransferase 1 ITS+ Supplemented insulin transferrine selenium LG-DMEM Low glucose Dulbecco's modified Eagle's medium MicroCT Micro-computed tomography MMP13 Matrix metalloproteinase-13 MNC Mononuclear cells MSC Mesenchymal stem cell