Pranav Bhagirath

145 Integrated whole-heart computational workflow for inverse potential mapping and personalized simulations A next step would be combining simulations with reconstructed IPM in order to non- invasively characterize tissue. Future directions Future research will focus on evaluating the IPM algorithm for patients undergoing catheter ablation for ectopic ventricular beats. The simulation algorithm will be further evaluated and optimized in patients with structural heart disease and arrhythmias. CONCLUSION The proposed FEM based whole-heart computational workflow offers an integrated platform for cardiac electrical assessment using IPM and simulations. The IPM algorithm can accurately reconstruct reliable cardiac activation sequences from BSP’s. The simulation model was able to incorporate patient-specific electrical parameters and rapidly performwhole-heart cardiac activation simulations. The use of MRI substantially contributes towards the clinical applicability. This workflow offers the prospect to improve patient selection and personalize therapeutic strategies for interventional electrophysiological procedures. Future studies should investigate the role of this innovative approach for analysis of complex atrial and ventricular arrhythmias.