Pranav Bhagirath

97 Left atrial sphericity: a promising parameter to predict response to ablation Table 1. Patient characteristics. N = 25 Nature of AF Paroxysmal (n=10) Persistent (n=15) Total duration of AF (days) 2333 ± 1817 1853 ± 1333 p = 0.48 Age (years) 64 ± 6.8 58 ± 8.3 Male (%) 70% 87% Hypertension (%) 40% 47% Body mass index 27 ± 5.5 29 ± 5.2 Body surface area 2 ± 0.2 2 ± 0.3 Anti-arrhythmic drugs - Sotalol or beta-blocker 80% 93% - Amiodarone 10% 13% - Flecainide 10% 7% Pre- (index) procedural LA sphericity 81.5 ± 3.3 84.7 ± 3 p = 0.02* Post-(index) procedural LA sphericity 81.2 ± 4.6 84.8 ± 2.6 p = 0.04* LA, left atrium. Pre Recurrence No-recurrence Post Spherical change Volume change +3.4% +19ml Spherical change Volume change -2% +19ml Figure 2. Comparison between structural and geometrical remodeling. A right sided view of the left atrial cavity depicting the discrepancy between changes in left atrial sphericity and volume following a repeat procedure. Top panel; a patient with recurrence of AF after repeat ablation with increased LASP (negative remodeling) and increased LA volume. Bottom panel; a patient without recurrence of AF after repeat ablation with decreased LASP (positive remodeling) and increased LA volume.